Buffalo Bills roster
| No. | Player | Pos | Status |
|---|---|---|---|
| 1 | Maxwell Hairston | CB | Active |
| 2 | DJ Moore | WR | Questionable |
| 3 | Damar Hamlin | S | Active |
| 4 | James Cook III | RB | Active |
| 5 | Joshua Palmer | WR | Questionable |
| 6 | Shane Buechele | QB | Practice squad |
| 7 | Ray Davis | RB | Active |
| 8 | Terrel Bernard | LB | Active |
| 9 | Bradley Chubb | LB | Active |
| 10 | Khalil Shakir | WR | Active |
| 11 | Kyle Allen | QB | Active |
| 13 | Skyler Bell | WR | Active |
| 14 | Tyrell Shavers | WR | Out |
| 15 | Greg Rousseau | LB | Active |
| 16 | Tyler Bass | PK | Active |
| 17 | Josh Allen | QB | Active |
| 19 | Greg Dortch | WR | Active |
| 20 | Frank Gore Jr. | RB | Practice squad |
| 21 | Davison Igbinosun | CB | Active |
| 23 | Dee Alford | CB | Questionable |
| 24 | Cole Bishop | S | Active |
| 25 | Geno Stone | S | Practice squad |
| 26 | Ty Johnson | RB | Active |
| 27 | Tre'Davious White | CB | Practice squad |
| 28 | Sam Franklin Jr. | S | News |
| 29 | Jalon Kilgore | S | Active |
| 31 | A.J. Woods | CB | Practice squad |
| 33 | Te'Cory Couch | CB | Active |
| 37 | Jordan Hancock | CB | Injured Reserve |
| 39 | Tommy Doman Jr. | P | Active |
| 41 | Kani Walker | CB | Active |
| 42 | Dorian Williams | LB | Active |
| 43 | Dorian Strong | CB | Out |
| 44 | Joe Andreessen | LB | Active |
| 45 | Shaq Thompson | LB | Practice squad |
| 47 | Christian Benford | CB | Active |
| 49 | Keonta Jenkins | LB | Practice squad |
| 51 | Mike Danna | DE | Active |
| 52 | Kaleb Elarms-Orr | LB | Active |
| 53 | Lloyd Cushenberry III | C | Active |
| 55 | Michael Hoecht | DE | Active |
| 56 | Javon Solomon | LB | Active |
| 60 | Ar'maj Reed-Adams | G | Active |
| 63 | Austin Corbett | C | Active |
| 64 | O'Cyrus Torrence | G | Active |
| 66 | Connor McGovern | C | Active |
| 67 | Travis Clayton | OT | Practice squad |
| 68 | Tylan Grable | OT | Active |
| 69 | Reid Ferguson | LS | Active |
| 70 | Alec Anderson | OT | Active |
| 72 | Phidarian Mathis | DT | Practice squad |
| 73 | Dion Dawkins | OT | Active |
| 74 | Jude Bowry | OT | Active |
| 77 | Chase Lundt | OT | Practice squad |
| 79 | Spencer Brown | OT | Questionable |
| 81 | Trent Sherfield | WR | Practice squad |
| 83 | Keleki Latu | TE | Active |
| 84 | Ja'Mori Maclin | WR | Practice squad |
| 85 | Jackson Hawes | TE | Active |
| 86 | Dalton Kincaid | TE | Active |
| 88 | Dawson Knox | TE | Active |
| 89 | Stephen Gosnell | WR | Practice squad |
| 90 | DeWayne Carter | DT | Active |
| 91 | Ed Oliver | DT | Active |
| 92 | Zane Durant | DT | Injured Reserve |
| 94 | Landon Jackson | DE | Active |
| 96 | Deone Walker | DT | Active |
| 97 | Greg Gaines | DT | Questionable |
| 98 | T.J. Sanders | DT | Active |
| 99 | TJ Parker | LB | Active |
| 0 | Keon Coleman | WR | Active |
| Brock Lampe | FB | Practice squad |